Several problems in drug ultrafine pulverizing machines also need to be solved
Chinese medicine ultrafine pulverizer is a Chinese medicine due to its crushing, so it is not destroyed on the basis of drug drug performance There are still some problems to make crushing. First solve the problem of powder aggregation. Airflow pulverizer and cyclone separator, dust collector, and airplane set into a set of pulverization systems. After the compressed air is dried, it is sprayed into the pulverizing chamber by the Lavar nozzle, and the material is repeatedly collided with the intersection of the multi-high pressure airflow.
The crushing material is pulverized after the fan pulling force Airflow movement to the grading area, under the power of high-speed rotation, the thick centrifugal force generated by the high-speed rotation, the fine particles that meet the particle size requirements are collected by the grading wheel into the cyclone and the dust collector, and the crude particles drops to the pulverizing region to continue pulverization. . The drug has increased significantly after ultra-micrising, and the surface can be high, and there is a strong interaction to achieve a stable tendency.
To prevent aggregation of the powder, it is in a single-scattered state, and suitable surface treatment and packaging techniques can be taken. Secondly solve the technical problems in the process of chemical extraction. The application of traditional Chinese medicine is no more approach: extracting and directly incompatation. From the extraction angle (Angle), there are two problems, which is the dispersion problem of the powder. The second is the gelatinization problem in the extraction process, which requires the extraction parameters (including the extraction temperature (including extraction temperature) by screening and optimization.
Temperature, extraction time, type of the type of medium, etc.) to solve. The technical problem in vitro dissolution determination is again solved. From the perspective of Chinese medicine directly into the medicine, the formulation of the ultra-fine pulverizer with Chinese medicine is used, and the core problem is the establishment of in vitro dissolution technology.
Measures to solve this problem are to perform screening of dissolution media (substances determined), the methodology of the dissolution method, and the target (TARGET AIM) component is integrated. Finally solve the technical problem of pharmacological verification. The ultrafine pulverizer is an apparatus for ultrafine pulverization of dry materials using air separation, heavy polishing, and shear. It consists of a cylindrical crushed chamber, a polishing wheel, a polishing rail, a fan, a material collection system, and the like. The pharmacodynamics is the most powerful verification means for preservation and enhance the efficacy of the effective ingredients after crushing of Chinese medicine. For Chinese medicine, it can significantly improve the pharmacological activity of the medicinal material, or to be verified (Resea)RCH).
At present, the ultrafine pulverizer of Chinese medicine begins to introduce airflow crushing technology. Traditional Chinese medicine through gas flow is limited only to some unique (interpretation: unique, special) expensive Chinese medicine, airflow pulverizer is an innovative crushing technology process, Bring a new look to traditional Chinese medicine processing and production (Produce).
The small Soviet research mill can be used to become an inert gas protection apparatus for an inert gas protection device such as a nitrogen gas such as nitrogen, a carbon dioxide gas. At present, the extraction method of the ultrafine pulverizer of the traditional Chinese medicine is getting more simplified, and the extraction time is getting shorter. The emergence of the ultra-fine pulverizer of the Chinese medicine is greatly saved, and the raw material utilization of Chinese medicine is improved.